Can Cannabinoid Ingredients Support Extracellular Matrix Integrity or Reduce Wrinkle Appearance?

Written by Synergy Life Science

November 22, 2023

Wrinkled Paper

As skincare ingredient science develops, so do the ingredients and products available on the market. Now, skincare products can address skin concerns, such as fine lines and wrinkles, on the cellular level. 

Products that support the extracellular matrix, like select ingredients in Synergy Life Science’s CannaSol products, can help create youthful-looking skin and minimize wrinkles from the inside out.

What is the Extracellular Matrix?

The extracellular matrix (ECM) is a complex network of molecules that surround, shape, and support cells throughout the body. This matrix comprises many complex chemicals that serve different functions in different parts of the body. 

What Does the Extracellular Matrix Do?

The extracellular matrix protects cells, providing a “scaffolding” and helping them hold their shape. It also actively affects the cells it surrounds, allowing them to perform their various functions.

How the Extracellular Matrix Fights Wrinkles and Premature Aging

One of the critical factors behind smooth, springy skin is the extracellular matrix. It provides a framework for skin cells, allowing them to bounce back and maintain a full appearance. The ECM also contains and helps form several chemicals essential to maintaining youthful skin, such as collagen and hyaluronic acid. 

As skin ages, the extracellular matrix breaks down. As it breaks down, the skin cells have less support, often leading to fine lines and a crepey appearance of the skin. However, modern skincare ingredients can help to support the extracellular matrix to allow skin to retain a youthful glow. 

4 Ways Hemp-Derived Cannabinoids Can Support Youthful Skin and a Healthy Extracellular Matrix

Some of the most effective tools in fighting premature skin aging are hemp-derived cannabinoids. These novel cannabis ingredients can support youthful-looking skin and a healthy extracellular matrix in many ways.

1. Cannabinoids May Provide Anti-Inflammatory Effects

Over the years, many studies have shown that cannabinoids likely have powerful anti-inflammatory effects when ingested or applied topically. Mature skin has a more challenging time defending itself from inflammation. The purported anti-inflammatory effects of hemp-derived cannabinoids can help to soothe inflamed skin and allow the skin’s natural properties, like the extracellular matrix, to function as nature intended.

2. Protect the Extracellular Matrix from UV Exposure With Cannabinoids

Exposure to harsh UV rays can damage the extracellular matrix and cause it to break down more quickly. Protecting the skin from excess sun exposure is essential to ensure the longevity and health of the extracellular matrix, and cannabis-derived formulations, such as Synergy Life Science’s line of CannaSol Active Esters, can provide sun protection and other benefits.

3. Cannabis Ingredients Could Provide Antioxidants to Support Aging Skin

Cannabis ingredients may also act as powerful antioxidants, supporting aging skin and helping fight free radicals threatening the skin’s health and youthful appearance. Free radicals can contribute to the breakdown of the extracellular matrix and premature aging in fine lines, wrinkles, and an uneven skin tone. Cannabis ingredients that provide antioxidant effects may, therefore, support the extracellular matrix and the appearance of youthful skin.

4. Novel Cannabinoid Ingredients Trigger Genetic Pathways Addressing the Extracellular Matrix

Novel and scientifically advanced cannabis skincare ingredients, like Synergy Life Science’s CannaSol line, can penetrate the skin and address the root of the problem by triggering the genetic pathways implicated in extracellular matrix integrity. 

Cannabinoid Ingredients to Strengthen the Extracellular Matrix

Synergy Life Science offers several ingredients that directly help support the extracellular matrix. 

  • CannaSol CB-C Ester: Triggers four genetic pathways that address extracellular matrix breakdown and integrity. This ingredient is moisturizing, conditioning, and has an SPF of 14.
  • CannaSol CB-D Ester: Triggers 19 genetic pathways, including those implicated in extracellular breakdown and integrity. It provides an excellent alternative to petrolatum products
  • CannaSol CB-S Ester: Tiggers an incredible 31 genetic pathways, inducing those involved in extracellular matrix breakdown. When applied topically, it provides a long-lasting cooling effect and has an SPF of 28.

All CannaSol products are pending GRAS approval, patent-pending, and extensively tested for safety. These cannabinoid ingredients are compatible with oil- and water-based systems and can provide gentle, effective support for the extracellular matrix. 

Where to Source CannaSol Active Esters

Synergy Life Science is the only source of CannaSol CB-S, CB-C, and CB-D esters. For more information about any of our products, help formulating them into products for your own company, or to request samples, contact Synergy Life Science today. 

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