Consumers increasingly report seeking cannabis and cannabinoids for sleep problems, and recent research advancements have shown an extensive relationship between the endocannabinoid system and the physiological regulation of sleep and wakefulness. With increased...

Skin delivery methods for topical cannabidiol (CBD) formulations are gaining popularity for pain, wound healing, anti-aging, and more. An advantage of topical cannabinoids is that they are not absorbed systemically, reducing the likelihood of psychoactive or unwanted...

Cannabinoid bioavailability is a crucial consideration in cannabis product formulations. If the cannabinoids in a product formulation are not sufficiently bioavailable, the product will not deliver the full dose and will not have its intended effects. What does...

The quality of a cannabis product hinges largely on the water solubilization of cannabinoids in the formulation. Cannabinoids are hydrophobic, meaning they do not naturally dissolve in water on their own. Improving the water solubility of cannabinoids is crucial to...

What Does Water Solubility Mean? Water solubility is the scientific term for the maximum amount of a particular substance or solute that can be dissolved in water as the solvent. The higher the substance's water solubility, the more efficiently it can dissolve in...

We mainly hear about the cannabinoids delta-9 tetrahydrocannabinol (delta-9 THC) and cannabidiol (CBD), but over 100 cannabinoids have been isolated from the cannabis plant. The 2018 Farm Bill legalized the sale of hemp-derived cannabinoids containing less than 0.3%...